Efficacy and Safety of Anti-Tubercular Regimens in Cirrhosis of Liver with Tuberculosis: A Randomised Controlled Trial
نویسندگان
چکیده
Methods: Two eighty nine (289) patients with cirrhosis of liver were evaluated for evidence of tuberculosis during a period of 24 months (March 2011 to March 2013) in a tertiary care centre. Patients with evidence of tuberculosis were randomised into two different ATT regimens (Regimen A and B) after exclusion. Regimen A included initial phase of isoniazid (INH), rifampicin (RIF), and ethambutol (EMB) for 2 months followed by a continuation phase of INH and RIF for 7 months, for a total of 9 months and regimen B included EMB, a fluoroquinolone (ofloxacin), and RIF for 12 months. All drugs were given on weight based daily doses.
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